Product Description
Entecavir is an antiviral medication used in the treatment of chronic hepatitis B virus (HBV) infection. Here’s a comprehensive description of Entecavir tablets:
- Generic Name: Entecavir
- Class:
- Antiviral Agent: Entecavir is a nucleoside analogue, specifically a guanine analogue.
- Brand Name:
- Entecavir is often marketed under various brand names.
- Indications:
- Treatment of chronic hepatitis B virus infection in adults and pediatric patients.
- Mechanism of Action:
- Entecavir is phosphorylated intracellularly to its active form, which competes with the natural building blocks of viral DNA.
- The active form inhibits the reverse transcription of viral DNA, disrupting the replication of the hepatitis B virus.
- Dosage:
- The dosage may vary based on the patient’s age, weight, renal function, and the specific condition being treated.
- Entecavir is typically administered orally in the form of tablets.
- Common Side Effects:
- Common side effects may include headache, fatigue, dizziness, and nausea.
- Serious side effects are rare but may include lactic acidosis and liver enzyme elevations.
- Precautions:
- Regular monitoring of liver function, renal function, and viral load is essential during treatment.
- Resistance to Entecavir may develop, and healthcare providers may order resistance testing if there is inadequate viral suppression.
- Contraindications:
- Hypersensitivity to Entecavir or any of its components.
- Pregnancy and Breastfeeding:
- The use of Entecavir during pregnancy is generally considered when the benefits outweigh potential risks.
- Entecavir is excreted in breast milk, and the decision to breastfeed should be made in consultation with a healthcare provider.
- Duration of Treatment:
- Entecavir is usually taken on a long-term basis for the treatment of chronic hepatitis B.
- Resistance Monitoring:
- Regular monitoring for the development of resistance is important, and adjustments in the treatment regimen may be necessary.
- Onset of Action:
- Entecavir starts to reduce viral load within weeks of starting treatment, but the duration of treatment may vary.
- Liver Function:
- Entecavir may improve liver function in individuals with chronic hepatitis B.
It’s crucial for individuals to use Entecavir under the guidance of a healthcare professional and to follow the prescribed dosage and instructions. Regular medical check-ups and communication with the healthcare provider are essential for the effective management of chronic hepatitis B.
