Product Description
Trastuzumab emtansine is a targeted therapy used in the treatment of certain types of breast cancer. It is commonly known by the brand name Kadcyla. Here’s a detailed overview of trastuzumab emtansine injection:
1. Indications:
- Trastuzumab emtansine is indicated for the treatment of HER2-positive breast cancer.
- It is specifically used in patients who have previously received trastuzumab (Herceptin) and a taxane chemotherapy.
2. Mechanism of Action:
- Trastuzumab emtansine is an antibody-drug conjugate. It combines trastuzumab, which targets HER2-positive cancer cells, with a chemotherapy drug called emtansine. This allows targeted delivery of chemotherapy to cancer cells, reducing damage to normal cells.
3. Administration:
- Trastuzumab emtansine is administered as an intravenous (IV) infusion by a healthcare professional in a hospital or clinic setting.
- The dosage and schedule depend on the specific type of breast cancer being treated and the patient’s overall health.
4. Side Effects:
- Common side effects include fatigue, nausea, headache, and musculoskeletal pain.
- Trastuzumab emtansine can also cause more serious side effects such as liver problems, bleeding, and cardiac toxicity.
5. Precautions and Monitoring:
- Patients receiving trastuzumab emtansine should be monitored closely for signs of liver problems, cardiac toxicity, and other potential side effects.
- Cardiac function is often assessed before and during treatment.
6. Pregnancy and Breastfeeding:
- Trastuzumab emtansine may harm an unborn baby, and effective contraception is recommended during treatment. It is not recommended for use during breastfeeding.
7. Storage:
- Trastuzumab emtansine injection should be stored according to the manufacturer’s instructions, typically at a controlled room temperature.
8. Contraindications:
- Individuals with a history of severe allergic reactions to trastuzumab or those with certain medical conditions may not be suitable candidates for this treatment.
9. Drug Interactions:
- Trastuzumab emtansine may interact with certain medications, so it’s important to inform healthcare providers about all medications being taken.
Always consult with healthcare professionals for personalized information and guidance, as specific details may vary based on the individual patient’s condition and the prescribing healthcare provider’s recommendations.
