Product Description
Oxaliplatin is a chemotherapy medication used in the treatment of colorectal cancer. It is a platinum-containing compound and belongs to the class of drugs known as platinum-based antineoplastic agents. Here’s a detailed overview of oxaliplatin injection:
1. Indications:
- Oxaliplatin is primarily used in combination with other chemotherapy drugs, such as 5-fluorouracil (5-FU) and leucovorin, for the treatment of advanced colorectal cancer.
2. Mechanism of Action:
- Oxaliplatin works by forming platinum-DNA adducts, leading to DNA cross-linking and inhibition of DNA replication. This interferes with the growth and division of cancer cells.
3. Administration:
- Oxaliplatin is administered intravenously (IV) by a healthcare professional in a hospital or clinic setting.
- The dosage and schedule depend on the specific type of cancer being treated, the patient’s overall health, and other factors.
4. Side Effects:
- Common side effects include peripheral neuropathy (tingling or numbness in the hands and feet), nausea, vomiting, diarrhea, and fatigue.
- Oxaliplatin can also cause myelosuppression, leading to lowered blood cell counts and an increased risk of infection and bleeding.
5. Precautions and Monitoring:
- Patients receiving oxaliplatin should be monitored closely for signs of peripheral neuropathy, myelosuppression, and other potential side effects.
- Neurological assessments are often conducted before and during treatment to manage and detect peripheral neuropathy.
6. Pregnancy and Breastfeeding:
- Oxaliplatin may harm an unborn baby, and effective contraception is recommended during treatment. It is not recommended for use during breastfeeding.
7. Storage:
- Oxaliplatin injection should be stored according to the manufacturer’s instructions, typically at room temperature, protected from light.
8. Contraindications:
- Individuals with a history of severe allergic reactions to oxaliplatin or those with certain medical conditions may not be suitable candidates for this treatment.
9. Drug Interactions:
- Oxaliplatin may interact with certain medications, so it’s important to inform healthcare providers about all medications being taken.
Always consult with healthcare professionals for personalized information and guidance, as specific details may vary based on the individual patient’s condition and the prescribing healthcare provider’s recommendations.
